Tidbits – Differential Expression Analysis for Pathways Very cool method which analyzes pathways rather than entire sets, and looks for the pathway which contributes most to the differential expression of the set. Their definition of pathway seems to be sets of 3 proteins/genes, and finding the most highly contributing “pathway” may not be the most […]
Tidbits – Interpretation of Genomic Variants Using a Unified Biological Network Approach “We find that functionally significant and highly conserved genes tend to be more central in physical protein-protein and regulatory networks. However, this is not the case for metabolic pathways, where the highly central genes have more duplicated copies and are more tolerant to […]
Remember that application for the ASBMB Hill Day? Well, I got accepted, have packed my bags and one of my new suits, and am now off to D.C.! It’s an exciting opportunity, and the experience of getting even just a little bit involved in the political process is well worth the travel, the expense of […]
Usually, Cracked posts some pretty hilarious content – typically on the more vulgar side, but hilarious nonetheless. But on happening to click on Cracked on accident, I found this article about why Mr. Rogers is so great. Not just great even, but the greatest American that ever was. He reminded us that every single one […]
My two favorite companies join forces. Now we just need Dropbox to offer more space..
“For many years, psychologists, following Freud, thought that people simply needed to express their anger and anxiety — blow off some steam — to be happier. But this is wrong…people who find meaning in adversity are ultimately healthier in the long run…resilient people are good at transforming negative feelings into positive ones.” -Emily Esfahani Smith […]
The moon landing was a longshot, but within reach – with significant capital, man, and willpower behind it, we achieved something incredible in that short decade when Kennedy declared that we will land a man on the moon. Currently, in my opinion, we have the same case for the life sciences. We are within reach […]
Two great papers from PLOS | Computational Biology on the topic. These papers go over both experimental (Part I) and computational (Part II) approaches to predicting protein to protein interactions. Really great reads to get a sense of how many resources there are to tackle this problem (hint: a lot). Also worth a look is […]
A really cool way to make interactive web apps using R as the backend. I can already see this being used in future lab meetings: “Oh, you want me to try this parameter? Why, let me just change it in my web app!” The potential use cases for this are fascinating.
The mailbox app has pretty much changed my working day. I used to spend good amounts of time rifling through the wall of text that was my inbox, for no reason at all. Just going up and down the inbox, checking over subject lines, making sure I hadn’t marked as read an important email, […]
